| Muscle | Innervation | Origin | Insertion | Action | Nerve Root |
| Thenar Muscles | |||||
| Abductor pollicis brevis (APB) | median | Scaphoid, trapezoid | base of proximal phalanx, radial side | abduct thumb | C8, T1 |
| Opponens pollicis | median | trapezium | thumb metacarpal | abduct, flex, med. Rotation | C8, T1 |
| Flexor pollicis brevis (FPB) | median(superficial head), ulnar(deep head) | trapezium, capitate | base of proximal phalanx, radial side | flex MCP | C7, C8 |
| Adductor pollicis | Ulnar | capitate, 2nd/3rd metacarpals | base of proximal phalanx, ulnar side | Adduct thumb | C8, T1 |
| Hypothenar Muscles | |||||
| Palmaris Brevis (PB) | ulnar | TCL, palmar aponeurosis | Ulnar palm | Retract skin | |
| Abductor dibiti minimi | ulnar | pisiform | base of proximal phalanx, ulnar side | abduct small finger | C8, T1 |
| Flexor digiti minimi brevis(FDMB) | Ulnar | hamate, TCL | base of proximal phalanx, ulnar side | flex MCP | C8, T1 |
| Opponens digiti minimi(ODM) | Ulnar | hamate, TCL | small finger metacarpal | abduct, flex, lat rotation | C8, T1 |
| Intrisinsic Muscles | |||||
| Lumbricals | median, ulnar(ulnar two) | flexor digitorum profundus(FDP) | lateral bands(radial) | extend PIP | |
| Dorsal interosseous(DIO)(DAB) | Ulnar | adjacent metacarpals | proximal phalanx base/extensor apparatus | abduct, flex MCP | C8, T1 |
| Volar interosseous(VIO) | Ulnar | adjacent metacarpals | proximal phalanx base/extensor apparatus | Adduct, flex MCP | C8, T1 |